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Pharmaceutical Solutions
Engineered for every payload, from small molecules to gene and cell therapy.
Small molecules tolerate almost any delivery path. Biologics, viral vectors and lipid nanoparticles do not. We engineer the needle and hub around the payload they carry, in partnership with pharmaceutical and biotechnology companies, CDMOs and CMOs, and compounding pharmacies.
Why the payload matters
The more advanced the therapy, the more fragile the payload
As therapeutics evolved from small-molecule chemistry toward complex biological molecules, they became dramatically more sensitive to how they are delivered.
| Modality | Structure | Viscosity | Shear sensitivity |
|---|---|---|---|
| Small molecules | Chemical synthesis | Very low | Negligible |
| Peptides | Short amino-acid chain | Low | Moderate |
| Biologics (mAbs) | Folded protein | High at concentration | High |
| Viral vectors (AAV) | Protein capsid shell | Medium, suspension | Extreme |
| mRNA therapies (LNP) | Lipid nanoparticle | Medium–high | Extreme |
Engineering response
The delivery risks we engineer against
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01Injection force: viscosity fights the needle
High-concentration biologics need significantly more force through a narrow bore, worse still at cold-chain temperatures. Our thin-wall geometry widens the internal bore without changing outer gauge, cutting the extrusion force needed.
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02Dead space: trapped fluid, lost dose
A standard hub can trap a meaningful share of a very small dose. Our low-dead-space hub geometry reclaims that volume, so more of what's drawn up actually reaches the patient.
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03Shear stress: unfolded proteins, ruptured capsids
Forcing a complex payload through a narrow gauge under pressure can deactivate proteins or damage viral shells and suspended cells. Smoothed flow paths and gentler bore transitions reduce the shear the payload sees.
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04Surface adhesion: payload lost to the walls
Rough internal surfaces can strip viral material and lipid nanoparticles from suspension, quietly lowering the delivered dose. Low-adhesion internal finishes are designed to keep payload in suspension from hub to tip.
Custom development
Fully custom, built to your molecule
Most of our device families began as a customer's specification, not a catalogue entry. If the geometry your molecule needs doesn't exist, we will build it.
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01Internal geometry & polymer
Flow paths and dead-space volume engineered around your fill volume and viscosity; hub materials matched to pressure and sterilization method.
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02Length & gauge
Intramuscular, subcutaneous, intravitreal and intrathecal routes each demand a different balance of penetration depth, gauge and flow.
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03Connection & fit
Custom fittings for proprietary delivery devices, auto-injectors or prefilled-syringe platforms; gauge and bore set together against your shear-rate tolerance.
Partnership
How we partner
Five stages, from brief to commercial supply.
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01Formulation & delivery brief
Viscosity, fill volume, sensitivity, route.
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02Device engineering
Hub, bore and gauge design and prototyping.
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03Bench validation
Flow, dose accuracy, injection force.
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04Pilot supply
Small-batch samples for your own testing.
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05Scale production
Commercial-volume manufacturing.
From concept through commercialization, we help connect formulation, procedure, device design, manufacturing, and regulatory considerations into a coordinated drug delivery strategy.
Next step
Bring your delivery challenge to us
Share your formulation, dose, delivery interface, work flow, and commercialization goals that need review. We can help assess feasibility, optimize device selection, define validation requirements, and support the path from development to commercial supply.